We present the first diffusion-based framework that can learn an unknown distribution using only highly-corrupted samples. This problem arises in scientific applications where access to uncorrupted samples is impossible or expensive to acquire. Another benefit of our approach is the ability to train generative models that are less likely to memorize any individual training sample, since they never observe clean training data. Our main idea is to introduce additional measurement distortion during the diffusion process and require the model to predict the original corrupted image from the further corrupted image. We prove that our method leads to models that learn the conditional expectation of the full uncorrupted image given this additional measurement corruption. This holds for any corruption process that satisfies some technical conditions (and in particular includes inpainting and compressed sensing). We train models on standard benchmarks (CelebA, CIFAR-10 and AFHQ) and show that we can learn the distribution even when all the training samples have 90\% of their pixels missing. We also show that we can finetune foundation models on small corrupted datasets (e.g. MRI scans with block corruptions) and learn the clean distribution without memorizing the training set.

Learning generative models from corrupted data is a fundamental yet persistently challenging task across scientific disciplines, particularly when access to clean data is limited or expensive. Denoising Score Distillation (DSD) \cite{chen2025denoising} recently introduced a novel and surprisingly effective strategy that leverages score distillation to train high-fidelity generative models directly from noisy observations. Building upon this foundation, we propose \textit{Restoration Score Distillation} (RSD), a principled generalization of DSD that accommodates a broader range of corruption types, such as blurred, incomplete, or low-resolution images. RSD operates by first pretraining a teacher diffusion model solely on corrupted data and subsequently distilling it into a single-step generator that produces high-quality reconstructions. Empirically, RSD consistently surpasses its teacher model across diverse restoration tasks on both natural and scientific datasets. Moreover, beyond standard diffusion objectives, the RSD framework is compatible with several corruption-aware training techniques such as Ambient Tweedie, Ambient Diffusion, and its Fourier-space variant, enabling flexible integration with recent advances in diffusion modeling. Theoretically, we demonstrate that in a linear regime, RSD recovers the eigenspace of the clean data covariance matrix from linear measurements, thereby serving as an implicit regularizer. This interpretation recasts score distillation not only as a sampling acceleration technique but as a principled approach to enhancing generative performance in severely degraded data regimes.

There is strong empirical evidence that the state-of-the-art diffusion modeling paradigm leads to models that memorize the training set, especially when the training set is small. Prior methods to mitigate the memorization problem often lead to a decrease in image quality. Is it possible to obtain strong and creative generative models, i.e., models that achieve high generation quality and low memorization? Despite the current pessimistic landscape of results, we make significant progress in pushing the trade-off between fidelity and memorization. We first provide theoretical evidence that memorization in diffusion models is only necessary for denoising problems at low noise scales (usually used in generating high-frequency details). Using this theoretical insight, we propose a simple, principled method to train the diffusion models using noisy data at large noise scales. We show that our method significantly reduces memorization without decreasing the image quality, for both text-conditional and unconditional models and for a variety of data availability settings.

We present the first diffusion-based framework that can learn an unknown distribution using only highly-corrupted samples. This problem arises in scientific applications where access to uncorrupted samples is impossible or expensive to acquire. Another benefit of our approach is the ability to train generative models that are less likely to memorize any individual training sample, since they never observe clean training data. Our main idea is to introduce additional measurement distortion during the diffusion process and require the model to predict the original corrupted image from the further corrupted image. We prove that our method leads to models that learn the conditional expectation of the full uncorrupted image given this additional measurement corruption.

We provide a framework for solving inverse problems with diffusion models learned from linearly corrupted data. Our method, Ambient Diffusion Posterior Sampling (A-DPS), leverages a generative model pre-trained on one type of corruption (e.g. image inpainting) to perform posterior sampling conditioned on measurements from a potentially different forward process (e.g. image blurring). We test the efficacy of our approach on standard natural image datasets (CelebA, FFHQ, and AFHQ) and we show that A-DPS can sometimes outperform models trained on clean data for several image restoration tasks in both speed and performance. We further extend the Ambient Diffusion framework to train MRI models with access only to Fourier subsampled multi-coil MRI measurements at various acceleration factors (R=2, 4, 6, 8). We again observe that models trained on highly subsampled data are better priors for solving inverse problems in the high acceleration regime than models trained on fully sampled data. We open-source our code and the trained Ambient Diffusion MRI models: https://github.com/utcsilab/ambient-diffusion-mri .